Postbiotics vs Probiotics vs Prebiotics
Quick Comparison
| Feature | Probiotics | Prebiotics | Postbiotics |
|---|---|---|---|
| What they are | Live beneficial bacteria | Fiber that feeds gut bacteria | Inactive bacterial byproducts (metabolites) |
| Stability | Require refrigeration, short shelf life | Shelf-stable | Shelf-stable, no refrigeration needed |
| Contains live bacteria | Yes | No | No |
| How they work | Colonize the gut with live organisms | Feed existing good bacteria | Deliver bioactive compounds directly |
| Research stage | Well-established | Well-established | Emerging, rapidly growing |
| Trial and error | Common | Minimal | Less trial and error |
What Are Probiotics?
Probiotics are live microorganisms often called good bacteria that are intended to maintain or improve the balance of bacteria in your gut. Found in fermented foods like yogurt, kefir, and kimchi, as well as in supplement form, probiotics work by introducing live bacteria into your digestive system.
What Are Prebiotics?
Prebiotics are types of dietary fiber that feed the beneficial bacteria already living in your gut. Found in foods like garlic, onions, bananas, and oats, prebiotics act as fertilizer for your microbiome.
What Are Postbiotics?
Postbiotics are the bioactive compounds produced when beneficial bacteria break down fibers during fermentation. According to the International Scientific Association for Probiotics and Prebiotics (ISAPP), a postbiotic is defined as a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host.
This makes postbiotics uniquely stable, shelf-stable, and less likely to cause digestive upset. Learn more about the science behind postbiotics
Which One Should You Choose?
Many people find that a combination approach works best. SecondKind Gut Balance is a postbiotic designed to support digestive ease. Mood Balance targets the gut-brain connection. The Gut and Mood Balance Bundle provides comprehensive gut-brain support.
Frequently Asked Questions
What is a postbiotic?
A postbiotic is a preparation of inanimate microorganisms and/or their components that confers a health benefit on the host, as defined by ISAPP.
Postbiotic vs probiotic what is the difference?
The main difference is that probiotics contain live bacteria, while postbiotics contain the inactive byproducts of bacterial fermentation. Postbiotics do not need refrigeration and are less likely to cause digestive upset.
Can I take postbiotics and probiotics together?
Yes, they work through different mechanisms. Consult your healthcare provider before starting a new routine.
Do postbiotics need to be refrigerated?
No, postbiotics are shelf-stable because they contain no live bacteria.