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Not another mood supplement.
Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance
  • Mood Balance

4.6/5 from verified customers

  • Calmer Mood
  • Stress Relief
  • Better Sleep
  • Gut + Immune Support
  • Clinically-backed Postbiotics
Mood Balance

Mood Balance

You tried the mood supplement. You still didn’t feel like yourself.
With Postbiotics + saffron, Mood Balance supports mood through the gut-brain connection.*

Purchase Options:
60-Day Risk-free Guarantee

60-Day Risk-free Guarantee

Free shipping on orders $60+ and subscriptions

Free shipping on orders $60+ and subscriptions

<p><strong>Why Postbiotics?</strong></p>

Why Postbiotics?

Daily Postbiotic support for:*

Emotional Balance
Emotional Balance
Stress Relief
Stress Relief
Mental Clarity
Mental Clarity
Sleep
Support
Sleep
Support
Non-Habit Forming
Non-Habit Forming
Why Postbiotics?

This is not another mood supplement. It’s Postbiotics - what your gut can use right away, so it can get to work faster.*

Postbiotics are the beneficial compounds probiotics produce - and the part your body actually uses.* While probiotics rely on live bacteria surviving digestion, postbiotics skip the middleman and deliver those beneficial compounds directly.*

The result is more direct, consistent support for mood, emotional balance, and mental clarity through the gut-brain axis.*

And because your gut is your second brain, that support can help influence how you feel every day - from calm and clarity to resilience, focus, and overall balance.*

Why SecondKind is different:

BiomeBalance™, our patented postbiotic complex, delivers clinically studied postbiotics designed to support gut balance and gut-brain signaling.* Paired with clinically studied saffron extract, Mood Balance helps support a calmer, clearer, more steady you - with meaningful support many people feel within weeks, and deeper benefits that continue building over time.*
Who It’s For

Mood Balance is for anyone who

  • Feels emotionally off, overwhelmed, or more irritable than usual
  • Struggles with occasional anxiety (from day-to-day life), brain fog, or mental fatigue
  • Wants to feel more emotionally balanced without relying on habit-forming pharmaceuticals
  • Needs support unwinding at night without feeling groggy the next morning
  • Values clinically studied, gut-connected ingredients for mood and mental clarity
  • Is ready to feel calmer, clearer, and more like themselves again
Ingredients

Built on the mood-regulating benefits of BiomeBalance™, Mood Balance combines science-backed postbiotics, with calming botanicals that work in harmony to support emotional wellbeing and focus.

  • Saffron Extract: Clinically studied for its ability to uplift mood, reduce anxiety, and promote emotional wellbeing.
  • Lemon Balm: A calming botanical that help soothe the nervous system and support a more relaxed, focused state.
  • Passionflower: Ease tension and support emotional resilience during times of stress.

    Clinically Studied Postbiotics

    Our BiomeBalance™ complex uses patented, research-backed postbiotics like Totipro® and Bereum® - fermentation-derived compounds your body can use right away.
  • Totipro®: Calms digestive distress, supports immune defenses, and promotes a balanced microbiome.
  • Bereum®: Clinically shown to reduce bloating, improve gut comfort, and deliver fast, noticeable digestive relief.
How to use Mood Balance

Take 1–2 capsules daily, ideally in the evening.

Use Mood Balance consistently as part of your daily routine. It can be taken with or without food.

For best results, take Mood Balance daily for at least 3 to 6 months to support benefits that build with consistency. No refrigeration necessary.

Daily serving: 1–2 capsules

Suggested use: 1–2 capsules in the evening

With or without food: Either is fine

Servings per bottle: 30

Refrigeration: Not required

Made for: Adults 18+
Supplement Facts

Supplement Facts Serving Size: 1 Capsule (1-2 times a day); 60 Servings Per Container:
BiomeBalance Postbiotic Complex 50mg [Soy Protein, Glucose, Saccharomyces cerevisiae,
Lactobacillus plantarum, Lactobacillus salivarius, Bifidobacterium infantis, Lactobacillus acidophilus,
Enterococcus faecalis]
Lemon Balm (Aerial Parts) – 350 mg (†)
Passionflower 4:1 Extract (Whole Plant) – 35 mg (†)
Saffron Flower Extract (0.3% Safranal) – 15 mg (†)
Melatonin – 5 mg (†)
Vitamin B6 (as Pyridoxine HCl) – 10 mg (588% DV)
Folate (as 400 mcg Folic Acid) – 680 mcg DFE (170% DV)
Magnesium (as Magnesium Hydroxide) – 100 mg (24% DV)


(†) Daily Value (DV) not established.

Other Ingredients: Hypromellose (Capsule), Microcrystalline Cellulose, Magnesium Stearate, Silicon
Dioxide, Soy
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Vegan

A black circle with a white DNA double helix symbol inside, crossed by a diagonal white line, indicating no DNA or non-GMO.

Non-GMO

A black circle with a white outline of three leaves inside, crossed by a diagonal line, representing a gluten-free or wheat-free symbol.

Gluten-Free

Doctor-Backed

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Clean Label &
Third Party-Tested

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No Refrigeration
Required

Clinically
Studied

Made in
the U.S.A.

Bundle & SAVE 15%

Gut and Mood Balance Bundle
Gut and Mood Balance Bundle
$84.99$99.90SAVE 15%

Doctor-Recommended

 — Dr. Stuart Weinberger, MD, Gastroenterologist
By centering its formulas around postbiotics, SecondKind is translating the latest gut-brain research into something

 — Dr. Stuart Weinberger, MD, Gastroenterologist

— Dr. Hyun Dong Shin, Ph.D., Independent Microbiologist & Postbiotic Expert
Bereum, used in SecondKind’s Gut Balance and Mood Balance, promotes the production of SCFAs to

— Dr. Hyun Dong Shin, Ph.D., Independent Microbiologist & Postbiotic Expert

— Dr. Zachary Schwartz, MD, Family Medicine
Gut health isn’t a niche topic anymore - it’s whole-body health, rooted in neuroscience and

— Dr. Zachary Schwartz, MD, Family Medicine

— Dr. Nancy Lin, PhD, Holistic Nutritionist
As a holistic nutritionist, I’ve seen countless gut supplements offer fake promises and deliver nothing….

— Dr. Nancy Lin, PhD, Holistic Nutritionist

— Sahar Berjis, RD, MPH, Functional Dietitian
Why wait for your gut bacteria to do all the work? Postbiotics skip the middleman - supporting a

— Sahar Berjis, RD, MPH, Functional Dietitian

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Feel the Difference
Within the First Bottle

Emotional
Balance

→ Supports a steady, more resilient mood throughout your day with noticeable results typically felt within 3-4 weeks.*

→ Supports a steady, more resilient mood throughout your day with noticeable results typically felt within 3-4 weeks.*

Mental
Clarity

→ Help reduce brain fog and restore calm focus

→ Help reduce brain fog and restore calm focus

Stress
Relief

→ Promotes a sense of ease without sedation or grogginess

→ Promotes a sense of ease without sedation or grogginess

Sleep
Support

→ Help you unwind at night, so you wake up more refreshed

→ Help you unwind at night, so you wake up more refreshed

Non-Habit
Forming

→ Safe for daily use with no dependency or tolerance buildup

→ Safe for daily use with no dependency or tolerance buildup

The Science Behind Gut Feelings

Your Gut Is
Your Second Brain

Your gut and brain are deeply connected through what science calls the gut-brain axis, a two-way superhighway that influences how you think, feel, and function. When this connection is out of sync, it can affect mood, focus, sleep, and even your ability to handle stress.

Mood Balance works at the source. Our BiomeBalance™ complex uses clinically studied Postbiotics to help restore healthy signaling between your gut and brain. This supports serotonin production, reduces stress responses, and promotes calm focus from within.

Paired with saffron extract, shown in studies to support emotional wellbeing, Mood Balance helps you feel lighter, more relaxed, and emotionally balanced, all through the power of your second brain.

Your gut produces:

91%

of your
serotonin

74%

of your
immune system

50%

of your
dopamine
A blurred, black and white close-up of a persons face with indistinct features and soft focus, conveying a sense of motion or emotional ambiguity.

Off-Balance

Brain fog, overwhelm, stress.
A close-up of a woman with dark skin smiling softly, eyes closed, and gently resting her face on her hand. She wears a black turtleneck and appears relaxed and content against a plain background.

Balanced

Clarity, calm, focus.

Backed by science. Proven in real life.

Gut Check

92%felt calmer in 2 weeks

88%noticed clearer thinking within 3 weeks

Why Postbiotics?

Because probiotics have to survive.
Postbiotics are ready to work.

Skip the fragile bacteria.

Most probiotics don't survive digestion.

The few that do create Postbiotics – the beneficial compounds your body actually uses.

SecondKind delivers Postbiotics directly to support a lighter gut, clearer mind, and more balanced you - fast.*

No fragile live bacteria. Just results.

Results You Feel Fast, Benefits That Last.

Mood

Feel balanced, uplifted, and emotionally steady.

Calm

Ease everyday stress and anxiety from within.

Steady Energy

Balanced energy without spikes or crashes.

A young woman with long black hair smiles brightly, looking upward. She has clear skin and natural makeup. The background is plain and light-colored.

Emotional Balance Starts Here

What to Expect ?

Week 1

First Signs

• Sleep feels smoother - you settle at night more easily.

• Your mind feels less “busy” in the evenings.

• Brain fog starts to lift; mornings feel lighter.*

Week 2

Balance Building

• A calmer emotional baseline emerges - you’re less reactive, more steady.

• Stress feels easier to navigate.

• You notice more relaxed, uplifted moments throughout your day.*

Week 3-4

Noticeable Difference

• A calmer emotional baseline emerges - you’re less reactive, more steady.

• Stress feels easier to navigate.

• You notice more relaxed, uplifted moments throughout your day.*

Month 2-3

Deep Reset

• Mood stability becomes your new normal - even during stressful weeks.

• A deeper sense of calm and clarity throughout the day.

• More restorative sleep and less grogginess in the morning.

• Focus improves; energy feels more purposeful.*

Month 4+

 Lasting Balance

• Your gut, brain, and emotional rhythms settle into alignment.*

• You feel more present - less noise, more calm.

• Ongoing, non-habit-forming support backed by clinical research.

Beyond Pre or Probiotics.
It’s Time For What’s Next.

Why Postbiotics Work Better

Prebiotics feed bacteria, probiotics are bacteria, but Postbiotics are what your body actually needs and uses right away.

*Some prebiotics (via short-chain fatty acids) and certain probiotics strains may also support gut lining, but postbiotics provide the most direct and consistent benefit.

Category
Postbiotics
(the harvest) 		Probiotics
(the seeds) 		Prebiotics
(the fertilizer)
Body-Ready & Usability
Digestive Comfort
Immunity
Mind & mood
Fast-Acting
Shelf-Stable
Whole-Body Wellness
Gut-Lining Support * *
Potency tick_icon (Trillion) (Billion)

*Some prebiotics (via short-chain fatty acids) and certain probiotics strains may also support gut lining, but postbiotics provide the most direct and consistent benefit.

Proven Results

Trusted Science

See The Science

  • Bereum, used in SecondKind’s Gut Balance and Mood Balance, promotes the production of SCFAs to optimize microbiome balance. This fundamental support strengthens physical health and helps manage stress, offering results you can actually feel. It's why I recommend SecondKind.

    — Dr. Hyun Dong Shin, Ph.D., Independent Microbiologist & Postbiotic Expert

  • Smiling older man with short gray hair and glasses, wearing a white shirt and a patterned tie, against a plain white background.

    By centering its formulas around postbiotics, SecondKind is translating the latest gut-brain research into something accessible for consumers. It reflects a more modern, science-forward understanding of digestive health.

     — Dr. Stuart Weinberger, MD, Gastroenterologist

  • A smiling man with a bald head and neatly trimmed beard, wearing a white medical coat and a gray patterned tie, in front of a neutral gray background.

    Gut health isn’t a niche topic anymore - it’s whole-body health, rooted in neuroscience and immunology. In clinical research, postbiotics are emerging as a direct, bioavailable way to influence gut health and systemic balance.

    — Dr. Zachary Schwartz, MD, Family Medicine

  • A woman with long, wavy black hair and a bright smile is wearing a sleeveless gray top. She is posing in front of a plain white background.

    As a holistic nutritionist, I’ve seen countless gut supplements offer fake promises and deliver nothing…. ineffective results. SecondKind stands apart because it’s postbiotic-first - finally, a solution that aligns with what the science tells us the body truly needs.

    — Dr. Nancy Lin, PhD, Holistic Nutritionist

  • Why wait for your gut bacteria to do all the work? Postbiotics skip the middleman - supporting a happier gut, stronger immunity, and better wellness from the inside out.

    — Sahar Berjis, RD, MPH, Functional Dietitian

Who It's For

Mood Balance is
for anyone who

  • Feels emotionally off, overwhelmed, or more irritable than usual
  • Struggles with occasional anxiety, brain fog, or mental fatigue
  • Wants to feel more emotionally balanced without relying on habit-forming pharmaceuticals
  • Needs support unwinding at night without feeling groggy the next morning
  • Values clinically studied, gut-connected ingredients for mood and mental clarity
  • Is ready to feel calmer, clearer, and more like themselves again
banner_image

Why SecondKind

You’ve tried probiotics.
Now try what actually works.

Grounded
in research

→ Made with clinically studied ingredients,
backed by science.

→ Made with clinically studied ingredients,
backed by science.

Feel it in days or weeks,
not months

→ Many notice a difference
within the first bottle.

→ Many notice a difference
within the first bottle.

No fillers,
no fluff

→ Clean formulas with only
targeted ingredients.

→ Clean formulas with only
targeted ingredients.

BiomeBalance™
Postbiotics, Perfected.

Patented, clinically studied blend delivering trillions of bioactives. It took years of research to develop the right combination and clinical dosing of Postbiotics that actually work. Designed to work fast to support your second brain for clarity, calm, and resilience.

Our Clinically Studied Postbiotics
BiomeBalance uses patented, research-backed postbiotics like Totipro®, EpiCor®, and Bereum® - fermentation-derived compounds your body can use right away.

✓ Each one is shelf-stable, clinically validated, and precisely formulated.

Totipro®

→ Clinically shown to relieve bloating and gut discomfort, ideal for daily gut balance or travel relief.

→ Calms digestive distress, supports immune defenses, and promotes a balanced microbiome.

→ Clinically studied Totipro® supported bowel regularity in 30 days and promoted beneficial gut bacteria.

Source: Kuo et al.,Lin et al., Journal of Pure and Applied Microbiology (2022)

EpiCor®

→ A whole-food fermentate packed with metabolites that strengthen gut lining, boost resilience, and help you stay well year-round.

→ EpiCor® was shown to reduce cold and flu symptom days by 17% in a 12-week randomized, placebo-controlled trial.

Source: Moyad et al., Urologic Nursing (2008)

Bereum®

→ Clinically shown to reduce bloating, improve gut comfort, and deliver fast, noticeable digestive relief.

→Clinically studied Bereum® postbiotics significantly improved gastrointestinal symptoms, perceived stress, and digestive-related quality of life, in an 84 day study.

Source: Bereum Human Clinical Study Summary for beLP1® and EF-2001®

Frequently Asked
Questions

What is Mood Balance?

Mood Balance is a postbiotic-first supplement formulated with BiomeBalance™ plus clinically studied botanicals like lemon balm, saffron, and passionflower - designed to support stress resilience, mood balance, and mental clarity.
How is this different from a probiotic?

Unlike probiotics, which rely on live bacteria that may not survive the gut, Mood Balance delivers postbiotics—bioactive compounds your body can use immediately, with fast-acting effects on gut-brain health.
When will I feel a difference?

Most people feel a shift in mood or clarity within days and weeks, not months, thanks to the “Feel It Fast” formula that combines postbiotics with calming botanicals.

Week 1: Early ease  - less bloating and digestive tension.
Weeks 2–3: Energy steadies, clarity lifts, and your gut rhythm begins to balance.
Month 1–2: Mood, focus, and immune balance feel more predictable.
Month 3+: Long-term harmony - gut, brain, and body in sync, for whole body health.
(Consistent daily use builds lasting gut resilience.)
How do I take Mood Balance?

Take 1 capsule, 1–2 times daily, ideally in the evening to align with your body’s natural relaxation rhythms.
Is it safe for daily use and use with other supplements or medications?

Mood Balance is designed for consistent, daily use and formulated with clinically studied postbiotic compounds that support the gut–brain connection.

Because postbiotics aren’t live bacteria, they’re stable, gentle, and well-tolerated - making them suitable for everyday support.

Every batch is third-party tested for quality and purity, and our ingredients are selected based on clinical research - not trends.

As with any supplement, we recommend consulting your healthcare provider if you’re pregnant, breastfeeding, managing a medical condition.
Is Mood Balance vegan and allergen-friendly?

Yes. It is vegan, non-GMO, and free from gluten, artificial colors/flavors, sucrose, starch, wheat, corn, gelatin, and nuts. It does contain soy.
A hand holds a jar labeled Mood Balance by SecondKind, a postbiotic supplement for mood, stress support, and clarity. Two capsules are placed beside the jar on a white surface.

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