You have two brains.

One thinks. One feels.
Your first brain lives in your head. Your second lives in your gut. 
Science calls this the gut–brain axis.

The second brain (your gut) is home to trillions of microbes shaping your mood, energy, clarity, digestion, and immunity. But it’s not the microbes themselves that matter most. It’s what they make. The science-backed compounds called Postbiotics - your gut and brain use to stay in sync, supporting clarity, mood, and whole-body balance.

When Your Second Brain
Is In Balance

Clearer
mind

→ Less fog, sharper focus.

→ Less fog, sharper focus.

Brighter
mood

→ A balanced, more resilient outlook.

→ A balanced, more resilient outlook.

Calmer
digestion

→ Reduced bloating, smoother digestion, and feeling lighter.

→ Reduced bloating, smoother digestion, and feeling lighter.

Stronger
immunity

→ Immune + stress resilience.

→ Immune + stress resilience.

Reduced
Inflammation

→ A calmer baseline, better balance.

→ A calmer baseline, better balance.

What is the gut–brain axis?

Your gut and brain are in constant conversation, linked by what science calls the gut–brain axis. This two-way superhighway, led by the vagus nerve, sends signals in milliseconds and help regulate mood, energy, digestion, and emotional balance in real time.

When your gut is in balance, you feel it: Steady mood, clear focus, lasting energy. When it’s not, the signals get scrambled. You feel fatigued, stressed, foggy, and just off.

Your gut produces:

91%

of your
serotonin

50%

of your
dopamine

74%

of your immune
system

When your gut microbiome is out of
balance, you feel it everywhere.

Off-Balance

Brain fog, bloat, stress.

Balanced

Clarity, calm, focus.

It’s more than about digestion.
Your gut actually produces feelings.

Postbiotics. What Your Body Actually Uses.

Most wellness products focus on adding bacteria, also known as probiotics. But your body doesn’t use the bacteria themselves. It uses the healthy metabolites they produce. These are bioactive compounds your body can actually use. That’s what Postbiotics are. They skip the middleman by delivering the benefits directly, even when prebiotics and probiotics might not survive digestion. The end result of healthy gut activity.

Short-chain fatty acids that nourish your gut lining.

Neuroactive compounds that help regulate mood.

Immune-supportive molecules that lower stress signals.

Why Postbiotics Work Better

Prebiotics feed bacteria, probiotics are bacteria, but Postbiotics are what your body actually needs and uses right away.

*Some prebiotics (via short-chain fatty acids) and certain probiotic strains may also support gut lining, but postbiotics provide the most direct and consistent benefit.

Category
Postbiotics
(the harvest)
Probiotics
(the seeds)
Prebiotics
(the fertilizer)
Body-Ready & Usability
Digestive Comfort
Immunity
Mind & Mood
Fast-Acting
Shelf-Stable
Whole-Body Wellness
Gut-Lining Support * *
Potency (Trillions) (Billions)

*Some prebiotics (via short-chain fatty acids) and certain probiotic strains may also support gut lining, but postbiotics provide the most direct and consistent benefit.

BiomeBalance
Postbiotics, Perfected.

Patented, clinically studied blend delivering trillions of bioactives. It took years of research to develop the right combination and clinical dosing of Postbiotics that actually work. Designed to work fast to support your second brain for clarity, calm, and resilience.

Our Clinically Studied Postbiotics
BiomeBalance uses patented, research-backed postbiotics like Totipro®, EpiCor®, and Bereum® - fermentation-derived compounds your body can use right away.

✓ Each one is shelf-stable, clinically validated, and precisely formulated.

→ No refrigeration required

Totipro®

→ Calms digestive distress, supports immune defenses, and promotes a balanced microbiome.

→ Clinically shown to relieve bloating and gut discomfort, ideal for daily gut balance or travel relief.

EpiCor®

→ A whole-food fermentate packed with metabolites that strengthen gut lining, boost resilience, and help you stay well year-round.

→ Reduces GI discomfort and supports immune defenses, shown to cut cold symptoms by up to 21%.

Bereum®

→ Clinically shown to reduce bloating, improve gut comfort, and deliver fast, noticeable digestive relief.

→ Help regulate mood and gut-brain signaling, supports emotional balance through the gut.

BiomeBalance
help turn gut chaos into calm.

Before

After

Active From Day One

How Postbiotics perform. Digestion in days, mood in weeks, resilience that lasts.

The Proof

Every claim backed by published studies.

  1. Mayer, E. A., & Tillisch, K. (2011). The brain–gut axis in abdominal pain syndromes. Annual Review of Medicine, 62, 381–396. https://doi.org/10.1146/annurev-med-012309-103958
  2. Carabotti, M., Scirocco, A., Maselli, M. A., & Severi, C. (2015). The gut–brain axis: Interactions between enteric microbiota, central and enteric nervous systems. Annals of Gastroenterology, 28(2), 203–209.
  3. Furness, J. B. (2012). The enteric nervous system and neurogastroenterology. Nature Reviews Gastroenterology & Hepatology, 9(5), 286–294. https://doi.org/10.1038/nrgastro.2012.32
  4. Strandwitz, P. (2018). Neurotransmitter modulation by the gut microbiota. Brain Research, 1693(Pt B), 128–133. https://doi.org/10.1016/j.brainres.2018.03.015
  5. Malashree, L., Angadi, V., Yadav, K. S., & Prabha, R. (2019). “Postbiotics” – one step ahead of probiotics. International Journal of Current Microbiology and Applied Sciences, 8(1), 2049–2053. https://doi.org/10.20546/ijcmas.2019.801.214
  6. Sorboni, S. G., Moghaddam, H. S., Jafarzadeh-Esfehani, R., & Soleimanpour, S. (2022). The gut microbiome in human neurological disorders. Clinical Microbiology Reviews, 35(1), e00338-20. https://doi.org/10.1128/CMR.00338-20
  7. Wang, Y., Kasper, L. H. (2014). The role of microbiome in central nervous system disorders. Brain, Behavior, and Immunity, 38, 1–12. https://doi.org/10.1016/j.bbi.2013.12.015
  8. Wang, Y. et al. (2020). SCFA-producing microbes and their role in gut-brain axis modulation. Trends in Microbiology, 28(10), 874-886. https://www.sciencedirect.com/science/article/pii/S2352289520300060
  9. Lin, W.-Y. et al. (2022). The function of mixed postbiotic PE0401 in improving intestinal health via elevating anti-inflammation, anti-oxidation, epithelial tight junction gene expression and promoting beneficial bacteria growth. Journal of Pure and Applied Microbiology, 16(3), 1771–1782.
  10. Kuo, Y.-W. et al. (2022). The microbial metabolites Totipro® PE0401 promoted probiotic bacteria growth and improved intestinal health in humans. ISAPP Poster Presentation.
  11. Moyad, M. A., et al. (2008). Effects of a modified yeast supplement on cold/flu symptoms. Urologic Nursing, 28(1), 50-55. https://asu.elsevierpure.com/en/publications/effects-of-a-modified-yeast-supplement-on-coldflu-symptoms
  12. Cargill. (n.d.). EpiCor® Winter Trial Abstract. https://www.cargill.com/food-beverage/na/epicor-winter-trial-abstract
  13. Lee, D. et al. (2022). Immune-enhancing effects of heat-treated Lactobacillus plantarum on NK cells and mucosal immunity. Nutrition Research, 102, 44–52. https://www.sciencedirect.com/science/article/pii/S1756464622003632
  14. Chen, L. et al. (2020). Effects of heat-killed Lactobacillus plantarum on irritable bowel syndrome symptoms: A randomized controlled trial. Journal of Functional Foods, 68, 103860. https://www.sciencedirect.com/science/article/pii/S2095809920303714
  15. Li, J. et al. (2024). Postbiotic Bifidobacterium breve 207-1 improves mood and stress response in healthy adults: A randomized trial. European Journal of Nutrition, 63, 2567–2585. https://link.springer.com/article/10.1007/s00394-024-03447-2
  16. Qian, Y. et al. (2024). Gut microbiota-derived indole-3-lactic acid alleviates depression via AhR signaling. Cell Reports Medicine, 5(7), 100545. https://www.cell.com/cell-reports-medicine/fulltext/S2666-3791%2824%2900545-7
  17. Morales-Ferré, C. et al. (2021). Effects of a postbiotic and prebiotic mixture on microbiota and immunity. Nutrients, 13(9), 2975. https://doi.org/10.3390/nu13092975
  18. Vinderola, G., Sanders, M. E., Salminen, S., & Szajewska, H. (2022). Postbiotics: The concept and their use in healthy populations. Frontiers in Nutrition, 9, 1002213. https://doi.org/10.3389/fnut.2022.1002213
  19. Kerksick, C. M., Moon, J. M., & Jäger, R. (2024). It’s dead! Can postbiotics really help performance and recovery? A systematic review. Nutrients, 16(5), 720.
  20. Zhou, C., Chen, P., Patil, S., & Dong, J. (2024). Unveiling the therapeutic symphony of probiotics, prebiotics, and postbiotics in gut-immune harmony. Frontiers in Nutrition. https://pmc.ncbi.nlm.nih.gov/articles/PMC10881654
  21. Prajapati, N. et al. (2024). Postbiotic production: Harnessing microbial metabolites for health applications. Frontiers in Microbiology, 14, 1358456. https://www.frontiersin.org/articles/10.3389/fmicb.2024.1358456/full
  22. mayouni Rad, A. et al. (2021). Postbiotics: mechanisms in allergy modulation and immunometabolism. Critical Reviews in Food Science and Nutrition, 61(3), 492–499.
  23. Park, S. J., Sharma, A., & Lee, H. J. (2023). Postbiotics and weight regulation: An emerging pathway. International Journal of Molecular Sciences, 24(7), 6414.
  24. Mayer, E. A. (2021). The gut–brain connection: How the hidden conversation within our bodies impacts our mood and health. Scientific American.
  25. SecondKind internal formulation data: BiomeBalance™ development dossier. (2024). Proprietary report demonstrating composition and clinical claims of Totipro®, EpiCor®, and Bereum postbiotics.












Trust your gut.
The science is clear.

You’ve got two brains. This is how you support both. SecondKind is the breakthrough that finally brings balance to your gut.