A first-of-its-kind, gentle daily Postbiotic supplement designed to reduce bloating and gas, while supporting gut health, microbiome balance, digestion, regularity and immunity - so you feel clearer, lighter, and more yourself from the very first bottle.* Powered by our patented BiomeBalance™ formula, it delivers a trillion clinically studied Postbiotics your body can actually use - for real results you can feel from the inside out.
Feel lighter, clearer, and balanced - fast.*
Pause or cancel anytime
10
% OFF future deliveries ($44.99
$49.99
per 1 month)
Free Shipping
Free Delivery
60-Day Money Back Guarantee
Vegan
Clinically
Studied
Non-GMO
No Refrigeration
Required
Gluten-Free
Kosher
Clean Label &
Third Party-Tested
Made in
the U.S.A.
Gut Health & Digestive Comfort
Supports considtent, daily digestive & gut health while helping maintain balanced gut microflora, a resilient microbiome, and a more comfortable, regular rhythm. Feel lighter, less bloated, and more comfortable enjoying the foods you love.*
Supports gut lining integrity and intestinal health*
Steady Energy
Promotes steadier daily energy, with less of the stop-and-start feeling that can throw off your day.*
Clarity
Supports the gut-brain connection for a more clear, balanced, and focused you.*
Immune Support
Helps support healthy immune function with clinically studied postbiotics.*
Whole-Body Wellness
Supports whole-body balance by nourishing the gut, your second brain, where so much of how you feel begins.*
Postbiotics are the clinically studied, ready-to-work compounds your gut actually uses for faster, more consistent support for a healthier, more comfortable gut.
Unlike probiotics, which rely on live bacteria surviving your digestive system, postbiotics are already active and ready for your body to use right away. That means no waiting for bacteria to colonize - just direct support your body can put to work immediately.
Your gut is your second brain - it affects mood, energy, focus, and immunity.
Postbiotics work differently.
BiomeBalance™, our patented postbiotic complex, contains clinically validated postbiotics designed to support gut balance and gut-brain signaling - with results many people feel within days or weeks, not months*.
The future of gut health isn’t more bacteria. It’s better delivery.
Gut Balance is for anyone who
Clinically Studied Postbiotics
Our BiomeBalance™ complex uses patented, research-backed postbiotics like Totipro®, EpiCor®, and Bereum® - fermentation-derived compounds your body can use right away.
Supplement Facts Serving Size: 2 Capsules; Servings Per Container: 30, BiomeBalance™ Postbiotic Complex (**) 1120 mg, Dry Fermentation of Saccharomyces cerevisiae, Lactobacillus plantarum, Lactobacillus salivarius, Bifidobacterium infantis, Lactobacillus acidophilus, Enterococcus faecalis, Soy Protein, Glucose,
**Daily Value (DV) not established.
Other Ingredients Hypromellose (Capsule), Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Promitor® Corn Fiber Product
Contains Soy
Digestion, debloat, and balance.
Strengthens defenses where it matters.
• A gentle settling in your gut - less pressure, less guessing.
• Early relief from bloating or discomfort.
• A subtle lift in clarity and steadier energy as your gut–brain connection responds.*
• Digestion starts to feel lighter and more predictable.
• You feel more “even” day-to-day - fewer dips, smoother energy.
• Your gut environment is shifting toward balance, helping your body respond better to stress and food.*
• Energy feels grounded, not up-and-down.
• Bloating continues to ease; your gut rhythm feels more natural.
• Everyday resilience strengthens - you bounce back from busy days more easily.
• Foods that used to bother you feel easier to handle.*
• Your microbiome becomes more stable, even if your schedule or diet gets messy.
• You feel clearer, lighter, and more consistently energized.
• Low-grade inflammation eases, supporting better clarity and vitality.*
• Your gut, brain, and immune system work together smoothly.
• Comfort becomes your new baseline - not something you have to chase.*
• Wellness feels easier and more automatic, supported by ongoing use.
Prebiotics feed bacteria, probiotics are bacteria, but Postbiotics are what your body actually needs and uses right away.
*Some prebiotics (via short-chain fatty acids) and certain probiotics strains may also support gut lining, but postbiotics provide the most direct and consistent benefit.
| Category | 
(the harvest) |
Probiotics (the seeds) |
Prebiotics (the fertilizer) |
|---|---|---|---|
| Body-Ready & Usability | |||
| Digestive Comfort | |||
| Immunity | |||
| Clarity | |||
| Fast-Acting | |||
| Shelf-Stable | |||
| Whole-Body Wellness | |||
| Gut-Lining Support | * | * | |
| Potency |
(Trillion)
|
(Billion) |
*Some prebiotics (via short-chain fatty acids) and certain probiotics strains may also support gut lining, but postbiotics provide the most direct and consistent benefit.
Bereum, used in SecondKind’s Gut Balance and Mood Balance, promotes the production of SCFAs to optimize microbiome balance. This fundamental support strengthens physical health and helps manage stress, offering results you can actually feel. It's why I recommend SecondKind.
— Dr. Hyun Dong Shin, Ph.D., Independent Microbiologist & Postbiotic Expert
By centering its formulas around postbiotics, SecondKind is translating the latest gut-brain research into something accessible for consumers. It reflects a more modern, science-forward understanding of digestive health.
— Dr. Stuart Weinberger, MD, Gastroenterologist
Gut health isn’t a niche topic anymore - it’s whole-body health, rooted in neuroscience and immunology. In clinical research, postbiotics are emerging as a direct, bioavailable way to influence gut health and systemic balance.
— Dr. Zachary Schwartz, MD, Family Medicine
As a holistic nutritionist, I’ve seen countless gut supplements offer fake promises and deliver nothing…. ineffective results. SecondKind stands apart because it’s postbiotic-first - finally, a solution that aligns with what the science tells us the body truly needs.
— Dr. Nancy Lin, PhD, Holistic Nutritionist
Patented, clinically studied blend delivering trillions of bioactives. It took years of research to develop the right combination and clinical dosing of Postbiotics that actually work. Designed to work fast to support your second brain for clarity, calm, and resilience.
Our Clinically Studied Postbiotics
BiomeBalance uses patented, research-backed postbiotics like Totipro®, EpiCor®, and Bereum® - fermentation-derived compounds your body can use right away.
✓ Each one is shelf-stable, clinically validated, and precisely formulated.
→ Calms digestive distress, supports immune defenses, and promotes a balanced microbiome.
→ Clinically studied Totipro® supported bowel regularity in 30 days and promoted beneficial gut bacteria. Source: Kuo et al.,Lin et al., Journal of Pure and Applied Microbiology (2022)
→ Clinically shown to relieve bloating and gut discomfort, ideal for daily gut balance or travel relief.
→ Clinically shown to reduce bloating, improve gut comfort, and deliver fast, noticeable digestive relief.
→ Help regulate mood and gut-brain signaling, supports emotional balance through the gut.
→ Clinically studied Bereum postbiotics significantly improved gastrointestinal symptoms, perceived stress, and digestive-related quality of life, in an 84 day study. Source: bereum Human Clinical Study Summary for beLP1® and EF-2001®
→ Clinically shown to reduce bloating, improve gut comfort, and deliver fast, noticeable digestive relief.
→ Help regulate mood and gut-brain signaling, supports emotional balance through the gut.
Gut Balance is a daily, science-backed postbiotic formula designed to support gut comfort, digestive balance, microbiome health, and whole-body wellness through the gut-brain connection. It’s made for people dealing with things like bloating, irregularity, digestive discomfort, brain fog, and feeling off - and want simple, daily support that goes beyond traditional probiotics.
Gut Balance is a better way to get consistent gut health, clarity and immunity.
Gut Balance uses clinically studied Postbiotics, not live bacteria. While probiotics rely on fragile live strains to survive digestion, postbiotics are stable, bioactive compounds your body can use more directly.
That’s what makes Gut Balance a great fit for people who want a gentler, more predictable, consistent way to support gut health, clarity, and overall balance.
BiomeBalance™ Postbiotic Complex (Soy Protein, Glucose, Dry Fermentation of Saccharomyces cerevisiae, Lactobacillus plantarum, Lactobacillus salivarius, Bifidobacterium infantis, Lactobacillus acidophilus, Enterococcus faecalis), Hypromellose (Capsule), Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Promitor® Corn Fiber.
Our BiomeBalance™ complex uses patented, research-backed postbiotics like Totipro®, EpiCor®, and Bereum® - fermentation-derived compounds your body can use right away.
Gut Balance is best for people who want support with:
It’s especially appealing for people who’ve tried probiotics before and either didn’t feel much or didn’t tolerate them well.
Gut Balance takes a different approach. Instead of relying on live bacteria, it delivers clinically studied postbiotic compounds that are more stable and designed to work with your body more directly. For many people, that means support that feels gentler, more consistent, and easier to notice.
Many people notice early support within the first bottle, especially with bloating, regularity, digestive comfort, clarity, and a greater sense of calm.
For deeper microbiome support, consistency matters. A simple way to think about it:
That’s why many customers choose subscription - it’s the easiest way to stay consistent and complete the full journey without gaps.
Many users report feeling lighter and less bloated within the first week, with continued benefits for digestion and immunity over time.
Week 1: Early ease - less bloating and digestive tension.
Weeks 2–3: Energy steadies, clarity lifts, and your gut rhythm begins to balance.
Month 1–2: Mood, focus, and immune balance feel more predictable.
Month 3+: Long-term harmony - gut, brain, and body in sync, for whole body health.
(Consistent daily use builds lasting gut resilience.)
Gut Balance is designed to be gentle. Because it uses postbiotics instead of live bacteria, many people find it easier to tolerate than traditional probiotics. While every body is different, it was formulated to support gut comfort without the common adjustment phase many people associate with probiotic products.
Gut Balance is powered by BiomeBalance™ - our blend of 3 clinically studied advanced postbiotics selected to support gut health, mood balance, immune function, and microbiome support.
The Postbiotics Inside BiomeBalance™:
Together, they’re designed to support gut comfort, a balanced microbiome, and whole-body balance from the inside out.
Take 2 capsules daily - 1 in the morning and 1 at night. Each bottle lasts 30 days, making it easy to stay consistent.
That’s what the guarantee is for. If Gut Balance isn’t the right fit, you’re covered by our 60-Day money-back guarantee, so you can try it with confidence.
